QUALITATIVE ANALYSIS OF PHYTOCHEMICALS IN THREE ANTI-DIABETIC MEDICINAL PLANTS OF BRAJ REGION OF UTTAR PRADESH

Diabetes mellitus is a group of chronic metabolic disorder characterized by hyperglycemia or increased blood glucose levels and eventually leads to damage of multiple body systems due to interference in carbohydrate, fat and protein metabolism following from comparable insufficiency of insulin oozing. Bioactive constituents revealed the presence of flavonoids, alkaloids, phenolic compounds, glycosides, sterols and terpenoids for treatment of diabetic activity in selected medicinal plants of Braj region of Uttar Pradesh such as Aloe vera, China rose and Jamun which possess ability to reduce blood glucose, urea, uric acid and creatinine and to increase insulin level, C-peptide and albumin control level. According to International Diabetes Federation (IDF), it is predicted that the number of diabetic patients in the World could reach up to 366 million by the year 2030. Aim of the present study showed the effect of different extracts such as aqueous, methanolic, ethanolic, acetone, chloroform and petroleum ether with various combinations to evaluate the presence of phytochemicals. Strongly presence of flavonoids with aqueous and methanolic leaves extracts according to other solvents in Aloe vera. In an aqueous leaves extracts of China rose, strongly presence of flavonoids and terpenoids according to other phytochemicals and alkaloids, flavonoids, phenolic compounds, terpenoids and glycosides in methanolic and ethanolic leaves extracts. Strongly presence of alkaloids, flavonoids, phenolic compounds, terpenoids and glycosides in an aqueous and methanolic leaves extracts of Jamun but the absence of tannin in all solvents. So, the aqueous, methanolic and ethanolic extracts are better for Aloe vera, China rose and Jamun for extraction of pytochemicals like alkaloids and flavonoids will be an effective tool for the treatment of diabetes and needs more study for drug development.