Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Assessment of multiple sclerosis using divided subtracted inversion recovery (dSIR) technique: a quantitative study
View through CrossRef
Motivation: The dSIR technique provides ultra-high image contrast; However, its usefulness for MS patients needs further study. Goal(s): This study aimed to evaluate dSIR measurements of deep gray matter (GM) nuclei and white matter (WM) lesions in MS patients and analyze their correlation with clinical assessments. Approach: Quantitative values for GM nuclei and WM lesions were measured from their dSIR images. Results: MS patients showed higher dSIR values in GM nuclei than healthy controls (HCs), enabling distinguishing patients from HCs with an area under the curve of about 0.81-0.92. The dSIR values of WM lesions moderately correlated with patients' cognitive and physical disability scores. Impact: The dSIR sequence can effectively quantitatively evaluate the abnormal changes of deep GM nuclei and WM lesions in MS patients and may be used for clinical monitoring of patients' cognitive and disability status.
Title: Assessment of multiple sclerosis using divided subtracted inversion recovery (dSIR) technique: a quantitative study
Description:
Motivation: The dSIR technique provides ultra-high image contrast; However, its usefulness for MS patients needs further study.
Goal(s): This study aimed to evaluate dSIR measurements of deep gray matter (GM) nuclei and white matter (WM) lesions in MS patients and analyze their correlation with clinical assessments.
Approach: Quantitative values for GM nuclei and WM lesions were measured from their dSIR images.
Results: MS patients showed higher dSIR values in GM nuclei than healthy controls (HCs), enabling distinguishing patients from HCs with an area under the curve of about 0.
81-0.
92.
The dSIR values of WM lesions moderately correlated with patients' cognitive and physical disability scores.
Impact: The dSIR sequence can effectively quantitatively evaluate the abnormal changes of deep GM nuclei and WM lesions in MS patients and may be used for clinical monitoring of patients' cognitive and disability status.
Related Results
Current therapeutic strategies for erectile function recovery after radical prostatectomy – literature review and meta-analysis
Current therapeutic strategies for erectile function recovery after radical prostatectomy – literature review and meta-analysis
Radical prostatectomy is the most commonly performed treatment option for localised prostate cancer. In the last decades the surgical technique has been improved and modified in or...
The relationship between ethnicity and Multiple Sclerosis characteristics in the United Kingdom: a UK MS Register study
The relationship between ethnicity and Multiple Sclerosis characteristics in the United Kingdom: a UK MS Register study
Abstract
Previous studies have suggested differences in Multiple Sclerosis severity between individuals from different ethnic backgrounds. Howeve...
Stochastic Rock Physics Inversion
Stochastic Rock Physics Inversion
Abstract
The purpose of this paper is to introduce a stochastic seismic inversion algorithm based on Markov Chain Monte Carlo Simulation. The suggested inversion ...
Inversion Using Adaptive Physics-Based Neural Network: Application to Magnetotelluric Inversion
Inversion Using Adaptive Physics-Based Neural Network: Application to Magnetotelluric Inversion
Abstract
In order to develop a geophysical earth model that is consistent with the measured geophysical data, two types of inversions are commonly used: a physics-ba...
Narrative review based on fingolimod therapy in pediatric MS
Narrative review based on fingolimod therapy in pediatric MS
The course of pediatric-onset multiple sclerosis and adult multiple sclerosis shows some clinical differences. The rate of having a second attack after the first clinical event is ...
Application of actuator dynamics inversion techniques to active vibration control systems and shake table testing
Application of actuator dynamics inversion techniques to active vibration control systems and shake table testing
Excessive vibrations problems usually arise in lightweight structures subjected to human actions. The active vibration absorber constitutes an effective solution to mitigate these ...
The Role of Gravity Waves in the Mesosphere Inversion Layers (MILs) over low-latitude (3–15° N) Using SABER Satellite Observations
The Role of Gravity Waves in the Mesosphere Inversion Layers (MILs) over low-latitude (3–15° N) Using SABER Satellite Observations
Abstract. The Mesosphere transitional region over low latitude is a distinct and highly turbulent zone of the atmosphere. A transition MLT region is connected with dynamic processe...
Validation of a High Contrast Technique and T1 Values Obtained by Divided Subtracted Inversion Recovery (dSIR)
Validation of a High Contrast Technique and T1 Values Obtained by Divided Subtracted Inversion Recovery (dSIR)
Motivation: To validate a 2 point high contrast T1 technique using the National Institute of Standards and Technology (NIST) T1 phantom. Goal(s): Qualitative results produced by th...