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Chromene-based fluorescent probes for sensing and bioimaging
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Chromene is an important motif in natural products and is the backbone for a range of fluorescent molecules. Chromene derivatives are particularly important for biological applications because of their distinctive photophysical and chemical properties. Recent research efforts have been focused on utilizing chromene-based probes motif for biological sensing applications. Most notably, the “thiol-chromene” click reaction realized the selective and rapid recognition of thiols. This Review presents the various chromene-based probes for a range of biologically relevant analytes. This includes examples of sensors for thiols, amino acids, hydrogen peroxide, and nitroreductase, as well as subcellular organelle-targeted probes.
Title: Chromene-based fluorescent probes for sensing and bioimaging
Description:
Chromene is an important motif in natural products and is the backbone for a range of fluorescent molecules.
Chromene derivatives are particularly important for biological applications because of their distinctive photophysical and chemical properties.
Recent research efforts have been focused on utilizing chromene-based probes motif for biological sensing applications.
Most notably, the “thiol-chromene” click reaction realized the selective and rapid recognition of thiols.
This Review presents the various chromene-based probes for a range of biologically relevant analytes.
This includes examples of sensors for thiols, amino acids, hydrogen peroxide, and nitroreductase, as well as subcellular organelle-targeted probes.
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