A COMPARATIVE CLINICAL STUDY TO EVALUATE POSTOPERATIVE ANALGESIA OF TWO DIFFERENT DRUGS DEXMEDETOMIDINE AND FENTANYL IN COMBINATION WITH 0.25% ROPIVACAINE FOR SURGICAL SITE INFILTRATION IN CASES OF MODIFIED RADICAL MASTECTOMY

Introduction: Pain is an expected side effect following surgery that frequently lasts for several days; if not addressed, it is linked to serious negative outcomes for the patient.Aims and Objectives: To compare the efcacy of Surgical site inltration 0.25% Ropivacaine with Dexmedetomidine (1mcg/Kg) and 0.25% Ropivacaine with Fentanyl (1mcg/Kg) postoperative pain relief in Modied Radical Mastectomy. Material and Method: The study was conducted in 70 female patients of age between 30-60 years of ASA grade I and II undergoing elective modied radical mastectomy surgeries. Patients were randomly divided into two groups. GROUP D– 0.25 % ropivacaine (20ml) + dexmedetomidine (1mcg/kg) + 0.9% normal saline and GROUP F– 0.25 % ropivacaine (20ml) + fentanyl (1mcg/kg) + 0.9% normal saline. Result: The mean time to rescue analgesia In Group D was 15.09±1.63 hours and in Group F was 8.63±1.26 hours. The difference in mean duration of rescue analgesia between the study groups was statistically highly signicant. Conclusion: Based on the present study we have concluded that adding dexmedetomidine to ropivacaine local wound inltration of the surgical site (modied radical mastectomy surgical site) prolongs the duration of analgesia in the postoperative period.