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FORMULATION AND EVALUATION OF VESICULAR DRUG DELIVERY SYSTEM OF MEFENAMIC ACID
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The objective of the present investigation was to develop niosomal based delivery system for application of mefenamic acid for treatment of inflammatory condition. The idea was to increase the bioavailability of drugs. Niosomes are known to present a solution to these side effects and the study proved that niosomes of mefenamic acid can provide improved drug bioavailability via sustained release of the drug. Among various formulations, CF7 was found to have a good release pattern and controlled release up to 24 hrs it could be suggested that the developed Pluronic P85 modified mefenamic acid niosomes could act as constant released niosomal carrier.
Keywords: Niosomes, mefenamic acid, surfactant, sustained release, Vesicular drug delivery
Current Research in Pharmaceutical Sciences
Title: FORMULATION AND EVALUATION OF VESICULAR DRUG DELIVERY SYSTEM OF MEFENAMIC ACID
Description:
The objective of the present investigation was to develop niosomal based delivery system for application of mefenamic acid for treatment of inflammatory condition.
The idea was to increase the bioavailability of drugs.
Niosomes are known to present a solution to these side effects and the study proved that niosomes of mefenamic acid can provide improved drug bioavailability via sustained release of the drug.
Among various formulations, CF7 was found to have a good release pattern and controlled release up to 24 hrs it could be suggested that the developed Pluronic P85 modified mefenamic acid niosomes could act as constant released niosomal carrier.
Keywords: Niosomes, mefenamic acid, surfactant, sustained release, Vesicular drug delivery.
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