Phytochemical Profiling and Evaluation of Antioxidant, Antimicrobial, and Thrombolytic Activities of Ethanolic Extract of Tarenna campaniflora Leaves

Discovery of the genus Tarenna campaniflora and its traditional uses was obtained by living in forest or semi-forest areas and by close observations of the indigenous populations. This study evaluated the phytochemical constituents, antioxidant potential, antimicrobial efficacy, and thrombolytic activity of ethanolic leaf extract of Tarenna campaniflora. Qualitative phytochemical screening revealed the presence of various bioactive metabolites. DPPH assay demonstrated notable antioxidant activity (IC50 = 0.877 µg/mL), comparable to ascorbic acid (IC50 = 0.839 µg/mL). Disc diffusion assay showed antimicrobial activity, with the highest inhibition against Escherichia coli (18 mm). The extract also exhibited clot lysis (22.42%), compared to streptokinase (31.17%). The findings support the therapeutic potential of T. campaniflora, warranting further pharmacological investigations.