Thirteen‐year follow up of isolated foveal retinoschisis in a 24‐year‐old woman

AbstractFoveal retinoschisis is rarely found in women. An 11‐year‐old girl, from non‐consanguineous parents, presented with bilateral visual loss from isolated foveal retinoschisis as confirmed by a normal fluorescein angiogram and characteristic optical coherence tomogram. Psychophysical and electrophysiological studies demonstrated mild contrast sensitivity loss, dyschromatopsia and normal full field electroretinographic responses. Visual acuity, foveal retinoschisis, electroretinography, electro‐oculography and visual evoked responses remained stable after 13 years but a reduction in pattern electroretinography amplitude was noted. No mutation was found in the coding regions of the RS1 gene. Isolated foveal retinoschisis may be a form of macular dystrophy. Longer‐term follow up may contribute to our understanding of this rare disease.