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Inadvertent High-Dose Exposure to Paliperidone Palmitate Depot: A Case Report
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Paliperidone palmitate is an atypical antipsychotic that can be
administered via intramuscular route in one monthly, three monthly and
six monthly preparations. Accidental overdose of paliperidone has been
reported on several occasions, however the existing published literature
only repots on overdoses occurring from cumulative doses over a period
of time. We report the case of a 55-year-old male with schizophrenia,
admitted with a psychotic relapse and, overdue for his paliperidone
three monthly long acting injectable (LAI) 350mg, who inadvertently
received 350mg of the 1-monthly preparation in one single
administration. Side effects were monitored over a three week period in
the inpatient setting during which there were only mild reports of
extra-pyramidal side effects. The patient continued to receive follow up
through the community mental health team for 6 months with no further
adverse effects reported.
Title: Inadvertent High-Dose Exposure to Paliperidone Palmitate Depot: A Case Report
Description:
Paliperidone palmitate is an atypical antipsychotic that can be
administered via intramuscular route in one monthly, three monthly and
six monthly preparations.
Accidental overdose of paliperidone has been
reported on several occasions, however the existing published literature
only repots on overdoses occurring from cumulative doses over a period
of time.
We report the case of a 55-year-old male with schizophrenia,
admitted with a psychotic relapse and, overdue for his paliperidone
three monthly long acting injectable (LAI) 350mg, who inadvertently
received 350mg of the 1-monthly preparation in one single
administration.
Side effects were monitored over a three week period in
the inpatient setting during which there were only mild reports of
extra-pyramidal side effects.
The patient continued to receive follow up
through the community mental health team for 6 months with no further
adverse effects reported.
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