Comparison of Efficacy of Conventional Wound Care with and without Intralesional Autologous Platelet Rich Plasma Injection towards Healing of Superficial Wound Dehiscence after Pfannenstiel Incision Surgery

Objective: To compare the efficacy of conventional wound care with and without autologous PRP injection in healing superficial wound dehiscence after Pfannenstiel incision surgery. Methodology: This prospective comparative study was conducted from March 2021 to February 2022 in the Gynae Department, Sir Ganga Ram Hospital, Lahore. Women 18-49 years of age presented with superficial wound dehiscence at the entire length of the Pfannenstiel incision were randomized into Group A (intralesional autologous PRP injection and conventional wound care) and Group B (conventional wound care alone). The wound was inspected for signs of infection, and the total wound area was calculated by multiplying both. Wound management was started by taking a swab for culture and sensitivity, and a single dose of intralesional autologous PRP was injected in a subcutaneous plane within half an hour of its preparation. Conventional wound care was continued during the hospital stay till the wound was clean and granulating. Secondary wound closure was done. The total duration of wound healing was noted for both groups. Results: The mean age of study participants was 31.5 ±4.29 years. The minimum duration of complete wound healing was 13 days, and the maximum was 22 days, with a mean + standard deviation of 18.05 + 2.78 days. The mean duration of complete healing in the PRP group was 15.80 + 1.83 days, while in the non-PRP group, it was 20.30 + 1.40 days, with a significant reduction(p=0.000). Conclusion: The autologous PRP injection significantly shortened the healing duration of superficial wound dehiscence after Pfannenstiel incision surgery.