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HYPOGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF SAURAUIA VULCANI KORTH. LEAVES
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Objective: The aim of this study was to investigate the hypoglycemic activity of ethanol extract of Saurauia vulcani Korth. leaves.Methods: S. vulcani Korth. leaf powder was extracted by maceration method with ethanol 96%. Hypoglycemic activity was examined on rats which is induced with streptozotocin 40 mg/Kg body weight (BW) at dose of 50; 100; and 200 mg/Kg BW.Results: Hypoglycemic activity of the extract in diabetic rats showed a significant reduction in blood glucose levels (p<0.001) at dosage 50 mg/Kg BW.Conclusion: The results reveal that ethanol extract of S. vulcani Korth. leaves has hypoglycemic activity. Our further study is to assess mechanism action as antidiabetic.
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Title: HYPOGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF SAURAUIA VULCANI KORTH. LEAVES
Description:
Objective: The aim of this study was to investigate the hypoglycemic activity of ethanol extract of Saurauia vulcani Korth.
leaves.
Methods: S.
vulcani Korth.
leaf powder was extracted by maceration method with ethanol 96%.
Hypoglycemic activity was examined on rats which is induced with streptozotocin 40 mg/Kg body weight (BW) at dose of 50; 100; and 200 mg/Kg BW.
Results: Hypoglycemic activity of the extract in diabetic rats showed a significant reduction in blood glucose levels (p<0.
001) at dosage 50 mg/Kg BW.
Conclusion: The results reveal that ethanol extract of S.
vulcani Korth.
leaves has hypoglycemic activity.
Our further study is to assess mechanism action as antidiabetic.
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