The high breathlessness, cough, fever treated by antibiotic therapy: Azithromycin – induced oral thrush

The oral thrush happens when a yeast disease creates within the mouth and on the tongue causing rich white knocks on the tongue, inward cheeks, gums, tonsils, marginally dying, torment, trouble gulping, irritability. A 35 years old female patient visited the hospital complaining of breathlessness, cough, fever the patient was treated with azithromycin -500mg PO once daily, co-trimoxazole -160mg+800mg, paracetamol -500mg PO (Per Os: by mouth, orally) t.d.s. (ter die sumendum three times a day) for ten days. After ten days of using azithromycin and co-trimoxazole, she developed severe oral thrush-white bumps, ulcers-involving bleeding, severe itching, difficulty swallowing. She completely left taking solid food because of severe itching and pain and she loses weight. As per our best knowledge, this was the first report, azithromycin and Co-trimoxazole induced oral thrush and it indicates that it should be considered as a possible side effect of azithromycin and Co-trimoxazole.