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The safety of statins in children

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AbstractCurrent American Academy of Pediatrics Guidelines recommended that statins should be considered as a first‐line agent in children as early as 8 years of age. The aim of our work is to assess the safety of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors in children with hypercholesterolaemia.ConclusionControlled studies in children show that statin monotherapy is efficacious, well tolerated and safe in the short‐time. Unfortunately, these studies have relatively short‐term follow‐up periods, and therefore, long‐term safety remains unclear.
Title: The safety of statins in children
Description:
AbstractCurrent American Academy of Pediatrics Guidelines recommended that statins should be considered as a first‐line agent in children as early as 8 years of age.
The aim of our work is to assess the safety of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors in children with hypercholesterolaemia.
ConclusionControlled studies in children show that statin monotherapy is efficacious, well tolerated and safe in the short‐time.
Unfortunately, these studies have relatively short‐term follow‐up periods, and therefore, long‐term safety remains unclear.

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