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HEPATOPROTECTIVE EFFECTS OF PHENOLIC GLYCOSIDES FROM THE METHANOL EXTRACT OF PHYSALIS ANGULATA
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By various chromatographic separations, four phenolic glycosides, methyl salicylate 2-O-triglycoside (1), icariside E5 (2), quercetin 3-O-rutinoside (3), and isorhamnetin 3-O-rutinoside (4) were isolated from the methanol extract of the whole plant of Physalis angulata. Their structures were determined by 1D-, 2D-NMR spectroscopic analyses and in comparison with the reported data. Compounds 3 exhibited significantly hepatoprotective activity with an EC50 value of 17.08 µg/mL. This is the first report of 1-4 from Physalis angulata.
Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
Title: HEPATOPROTECTIVE EFFECTS OF PHENOLIC GLYCOSIDES FROM THE METHANOL EXTRACT OF PHYSALIS ANGULATA
Description:
By various chromatographic separations, four phenolic glycosides, methyl salicylate 2-O-triglycoside (1), icariside E5 (2), quercetin 3-O-rutinoside (3), and isorhamnetin 3-O-rutinoside (4) were isolated from the methanol extract of the whole plant of Physalis angulata.
Their structures were determined by 1D-, 2D-NMR spectroscopic analyses and in comparison with the reported data.
Compounds 3 exhibited significantly hepatoprotective activity with an EC50 value of 17.
08 µg/mL.
This is the first report of 1-4 from Physalis angulata.
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