Javascript must be enabled to continue!
REVIEW: ACTIVITY OF DIOSGENIN COMPOUND AS ATHEROSCLEROSIS THERAPY
View through CrossRef
Atherosclerosis is a disease that causes inhibition of the stability of the cardiovascular system in the body. Cardiovascular disease remains at the top of the list of diseases that cause death. Therefore, cardiovascular disease therapy, including atherosclerosis, still needs to be developed to reduce the mortality rate associated with this disease. Several studies have shown that diosgenin compounds can be used as a therapy for atherosclerosis. The purpose of this study was to determine whether diosgenin compounds and their derivatives can be used for atherosclerosis therapy with various mechanisms of action related to the development of atherosclerosis. This article review was conducted using the article search method on Google Scholar, Pubmed, and Science Direct with various keywords. The results obtained are diosgenin and several diosgenin-derived compounds that can be used as therapies for atherosclerosis with several responses obtained from experiments using rats.
Keywords: diosgenin; atherosclerosis; diosgenin derivatives
Sekolah Tinggi Farmasi Muhammadiyah Cirebon
Title: REVIEW: ACTIVITY OF DIOSGENIN COMPOUND AS ATHEROSCLEROSIS THERAPY
Description:
Atherosclerosis is a disease that causes inhibition of the stability of the cardiovascular system in the body.
Cardiovascular disease remains at the top of the list of diseases that cause death.
Therefore, cardiovascular disease therapy, including atherosclerosis, still needs to be developed to reduce the mortality rate associated with this disease.
Several studies have shown that diosgenin compounds can be used as a therapy for atherosclerosis.
The purpose of this study was to determine whether diosgenin compounds and their derivatives can be used for atherosclerosis therapy with various mechanisms of action related to the development of atherosclerosis.
This article review was conducted using the article search method on Google Scholar, Pubmed, and Science Direct with various keywords.
The results obtained are diosgenin and several diosgenin-derived compounds that can be used as therapies for atherosclerosis with several responses obtained from experiments using rats.
Keywords: diosgenin; atherosclerosis; diosgenin derivatives.
Related Results
Evaluating the Science to Inform the Physical Activity Guidelines for Americans Midcourse Report
Evaluating the Science to Inform the Physical Activity Guidelines for Americans Midcourse Report
Abstract
The Physical Activity Guidelines for Americans (Guidelines) advises older adults to be as active as possible. Yet, despite the well documented benefits of physical activi...
Synthesis and Evaluation of Cytotoxicity of Carbon Dots Functionalized
with Diosgenin
Synthesis and Evaluation of Cytotoxicity of Carbon Dots Functionalized
with Diosgenin
Background:
Diosgenin is a plant-derived steroidal sapogenin, whose effectiveness has
been reported in the treatment of various cancer cells, but its poor bioavailability has alway...
Neuroprotective Role of Diosgenin, A NGF Stimulator, Against Aβ (1–42) Induced Neurotoxicity in Animal Model of Alzheimer’s Disease
Neuroprotective Role of Diosgenin, A NGF Stimulator, Against Aβ (1–42) Induced Neurotoxicity in Animal Model of Alzheimer’s Disease
Abstract
Diosgenin is a neurosteroid derived from the plants and has been previously reported for its numerous health beneficial properties, such as anti-arrhythmic, hypoli...
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy
Abstract
Diosgenin, a natural steroid saponin, holds promise as a multitarget therapeutic for various diseases, including neurodegenerative c...
Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen
Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen
Background: Diosgenin, a powerful compound found in fenugreek and Dioscorea villosa, has diverse pharmacological effects. This study examines the anticancer potential of diosgenin ...
Diosgenin in polyendocrine metabolic ovarian syndrome: modulation of insulin resistance, inflammation, steroidogenesis, and metabolic dysfunction
Diosgenin in polyendocrine metabolic ovarian syndrome: modulation of insulin resistance, inflammation, steroidogenesis, and metabolic dysfunction
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a complex endocrinopathy with characteristic features of hyperandrogenism, ovulatory dysfunction, insulin resistance, and obesity...
Comparative Computational Analysis of Antidiabetic Potential of Diosgenin, Costunolide and Eremanthin from Costus speciosus (Sri Lankan Thebu)
Comparative Computational Analysis of Antidiabetic Potential of Diosgenin, Costunolide and Eremanthin from Costus speciosus (Sri Lankan Thebu)
Costus speciosus is a medicinal plant used in Eastern medicine (also known as Asian medicine) due to its phytochemical content, which has been shown to significantly lower blood su...
Identification of potential genotypes of fenugreek in rainfed vertisols for yield and diosgenin content
Identification of potential genotypes of fenugreek in rainfed vertisols for yield and diosgenin content
The present study was undertaken for three years (2009-12) to evaluate thirteen promising genotypes from India for both yield and diosgenin content. Maximum yield was recorded in g...

