A Targeted Approach: Understanding the Role of Ginkgo Biloba in Varied Dementia Patient Profiles

With the burden of dementia growing worldwide and its increasing prevalence, there is an urgent need for treatments that can effectively target the main mechanisms of the neurodegenerative process [1]. A lot of hope lies in traditional herbal medicine, particulary Ginkgo Biloba, wich is believed to not only stop the neurodegenerative process, but also to alleviate the neuropsychiatric symptoms of dementia [2]. However, current literature tends to overlook the demographic-specific effects of Ginkgo Biloba, not clarifying the efficacy across varied patient profiles. In this context, we conducted a thorough search across multiple databases, focusing on Ginkgo Biloba impact age, sex, genetic phenotype and type of dementia. Our conclusions reaveled a varied efficacy between different demographic groups, with noticeable benefits in some populations or even fewer adverse effects in others. Particularly, we identified that groups with older adults and specific genetic markers exhibited the most significant improvements in cognition, signifying that there is a strong need for personalized therapeutic strategies, using the demographic considerations in clinical decision making. This review aims to highlight the benefits of herbal medicine, principally Ginkgo Biloba, in adapted dementia care, even though deeper research is needed to develop accurate treatment protocols for assorted patient populations.