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Cerebrospinal Fluid
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Evaluation of cerebrospinal fluid is of essential importance in the diagnosis of central nervous system infections, with a major role in the diagnosis of meningitis and encephalitis. In bacterial and viral meningitis, CSF evaluation is usually straightforward, and well-defined serological and molecular techniques are available for CSF examination in many of the more common viral encephalitides. This is in contrast to CSF evaluation in cases of tuberculous and chronic meningitis, in which organisms may be difficult to detect by culture or polymerase chain methods or antigen detection. This chapter first discusses the anatomy and physiology of CSF production, reviews concepts of CSF analysis, and then reviews CSF changes in the major categories of central nervous system infections.
Title: Cerebrospinal Fluid
Description:
Evaluation of cerebrospinal fluid is of essential importance in the diagnosis of central nervous system infections, with a major role in the diagnosis of meningitis and encephalitis.
In bacterial and viral meningitis, CSF evaluation is usually straightforward, and well-defined serological and molecular techniques are available for CSF examination in many of the more common viral encephalitides.
This is in contrast to CSF evaluation in cases of tuberculous and chronic meningitis, in which organisms may be difficult to detect by culture or polymerase chain methods or antigen detection.
This chapter first discusses the anatomy and physiology of CSF production, reviews concepts of CSF analysis, and then reviews CSF changes in the major categories of central nervous system infections.
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