Observation on the Clinical Efficacy of Zuojin Yifan Granules in the Treatment of Reflux Esophagitis (Liver Stomach Stagnation Heat Syndrome)

Objective: To observe the clinical efficacy of Zuojin Yifan Granules in the treatment of reflux esophagitis (liver stomach stagnation heat syndrome). Method: 108 patients with reflux esophagitis (liver stomach stagnation heat syndrome) were randomly divided into Group A, Group B, and Group C using a random number table, with 36 patients in each group. Group A received treatment with Zuojin Yifan Granules, Group B received treatment with Zuojin Yifan Granules combined with rabeprazole, and Group C received treatment with rabeprazole for 8 weeks. Clinical symptom scores between groups and within groups were compared, and the improvement of clinical symptoms and changes in esophageal mucosa under endoscopy were observed in patients. Result: Before treatment, there was no statistically significant difference in clinical symptom scores among the three groups (P>0.05). After treatment, the clinical symptom scores of the three groups improved compared to before treatment. The clinical symptom scores of Group B were lower than those of Group A and Group C (P<0.05), and the clinical symptom scores of Group A were lower than those of Group C (P<0.05). The total effective rate of clinical symptom improvement in Group B was higher than that in Group A (P<0.05), and the total effective rate of clinical symptom improvement in Group A after treatment was higher than that in Group C (P<0.05). The total effective rate of endoscopic efficacy in Group B was higher than that in Group A (P<0.05), and the total effective rate of endoscopic efficacy in Group A was higher than that in Group C (P<0.05). Conclusion: The clinical effect of Zuojin Yifan Granules in the treatment of reflux esophagitis (liver stomach stagnation heat syndrome) is ideal, which can significantly improve clinical symptoms and enhance the endoscopic efficacy of patients.