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Analysis of corrected QT dispersion, tp-e values in small heart syndrome patients

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Abstract Funding Acknowledgements Type of funding sources: None. Background and objectives We aimed to evaluate the marker of ventricular arrhythmias such as Tp-e/QT, Tp-e/QTc, Tp-e/JT and Tp-e/JTc ratios in ‘Small Heart Syndrome’ female patients and also aimed to evaluate the association between ‘small heart syndrome’ and fibromyalgia in female patients. Methods A total of 94 female, including 47 small-heart and 47 normal-heart patients, who applied from March 2018 to February 2020 and who were examined by a physical therapy and rehabilitation specialist, were included in the study by calculating their cardiothoracic ratios (CTR) from the chest x-ray. QTmax, QTmin,QRS, JT and Tp-e intervals were measured. In addition, Tp-e/QTmax, Tp-e/QTc max, Tp-e/JT and Tp-e/JTc rates and QTc max, QTc min, cQTd and JTc intervals were calculated. Results cQTd (24,246 ± 9,046 ms vs. 35,495 ± 14,358 ms, p < 0.001), Tp-e (67,32 ± 11,661 ms vs. 72,67 ± 11,028 ms, p = 0.04), Tp-e/QTc max (0,166 ± 0.028 vs. 0.181 ± 0.027, p = 0,012), Tp-e/JTc (0,214 ± 0.038 vs. 0.232 ± 0.034, p = 0,022) values were significantly higher in small heart patient group. QT min (330,68 ± 26,611 ms vs. 323,04 ± 30,829 ms, p = 0,202) values were significantly lower in patient group. Conclusion Compared to control group potential ECG repolarization predictors were significantly increased in ‘Small Heart Syndrome’ patients. TableElectrocardiographic findings o Control group(n = 47) Patient group(n = 47) P value Heart rate, bpm 87,81 + 15,532 83,81 + 14,372 0,223 QRS; ms 83,23 + 6,948 81,91 + 10,052 0,206 QT max; ms 354,93 + 26,796 358,54 + 28,434 0,528 QT min; ms 330,68 + 26,611 323,04 + 30,829 0,202 JT; ms 265,7 + 25,16 271,88 + 23,104 0,218 QTc max; ms 403,59 + 18,208 400,20 + 18,336 0,371 QTc min; ms 379,34 + 20,064 364,71 + 23,149 0,004* JTc; ms 314,37 + 21,325 313,55 + 22,526 0,856 cQTd; ms 24,246 + 9,046 35,495 + 14,358 <0,001* Tp-e; ms 67,32 + 11,661 72,67 + 11,028 0,040* Tp-e/QT max 0,190 + 0,034 0,203 + 0,031 0,063 Tp-e/QTc max 0,166 + 0,028 0,181 + 0,027 0,012* Tp-e/JT 0,255 + 0,047 0,267 + 0,036 0,295 Tp-e/JTc 0,214 + 0,038 0,232 + 0,034 0,022*
Oxford University Press (OUP)
Title: Analysis of corrected QT dispersion, tp-e values in small heart syndrome patients
Description:
Abstract Funding Acknowledgements Type of funding sources: None.
Background and objectives We aimed to evaluate the marker of ventricular arrhythmias such as Tp-e/QT, Tp-e/QTc, Tp-e/JT and Tp-e/JTc ratios in ‘Small Heart Syndrome’ female patients and also aimed to evaluate the association between ‘small heart syndrome’ and fibromyalgia in female patients.
Methods A total of 94 female, including 47 small-heart and 47 normal-heart patients, who applied from March 2018 to February 2020 and who were examined by a physical therapy and rehabilitation specialist, were included in the study by calculating their cardiothoracic ratios (CTR) from the chest x-ray.
QTmax, QTmin,QRS, JT and Tp-e intervals were measured.
In addition, Tp-e/QTmax, Tp-e/QTc max, Tp-e/JT and Tp-e/JTc rates and QTc max, QTc min, cQTd and JTc intervals were calculated.
Results cQTd (24,246 ± 9,046 ms vs.
35,495 ± 14,358 ms, p < 0.
001), Tp-e (67,32 ± 11,661 ms vs.
72,67 ± 11,028 ms, p = 0.
04), Tp-e/QTc max (0,166 ± 0.
028 vs.
0.
181 ± 0.
027, p = 0,012), Tp-e/JTc (0,214 ± 0.
038 vs.
0.
232 ± 0.
034, p = 0,022) values were significantly higher in small heart patient group.
QT min (330,68 ± 26,611 ms vs.
323,04 ± 30,829 ms, p = 0,202) values were significantly lower in patient group.
Conclusion Compared to control group potential ECG repolarization predictors were significantly increased in ‘Small Heart Syndrome’ patients.
TableElectrocardiographic findings o Control group(n = 47) Patient group(n = 47) P value Heart rate, bpm 87,81 + 15,532 83,81 + 14,372 0,223 QRS; ms 83,23 + 6,948 81,91 + 10,052 0,206 QT max; ms 354,93 + 26,796 358,54 + 28,434 0,528 QT min; ms 330,68 + 26,611 323,04 + 30,829 0,202 JT; ms 265,7 + 25,16 271,88 + 23,104 0,218 QTc max; ms 403,59 + 18,208 400,20 + 18,336 0,371 QTc min; ms 379,34 + 20,064 364,71 + 23,149 0,004* JTc; ms 314,37 + 21,325 313,55 + 22,526 0,856 cQTd; ms 24,246 + 9,046 35,495 + 14,358 <0,001* Tp-e; ms 67,32 + 11,661 72,67 + 11,028 0,040* Tp-e/QT max 0,190 + 0,034 0,203 + 0,031 0,063 Tp-e/QTc max 0,166 + 0,028 0,181 + 0,027 0,012* Tp-e/JT 0,255 + 0,047 0,267 + 0,036 0,295 Tp-e/JTc 0,214 + 0,038 0,232 + 0,034 0,022*.

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