Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Palladium/Xu-Phos Catalyzed Enantioselective Intramolecular Heck Reaction of Unactivated Alkenes
View through CrossRef
A highly enantioselective palladium-catalyzed intramolecular Heck
reaction of unactivated alkenes is developed, which provides a powerful
route to access a broad range of chiral
3,3-disubstituted-2,3-dihydrobenzofurans bearing all-carbon quaternary
stereocenter of interest in pharmaceutical research. Its salient
features include high yield, excellent chemo- and enantioselectivity,
mild condi-tions, a broad substrate scope as well as versatile
transformations of the product.
Title: Palladium/Xu-Phos Catalyzed Enantioselective Intramolecular Heck Reaction of Unactivated Alkenes
Description:
A highly enantioselective palladium-catalyzed intramolecular Heck
reaction of unactivated alkenes is developed, which provides a powerful
route to access a broad range of chiral
3,3-disubstituted-2,3-dihydrobenzofurans bearing all-carbon quaternary
stereocenter of interest in pharmaceutical research.
Its salient
features include high yield, excellent chemo- and enantioselectivity,
mild condi-tions, a broad substrate scope as well as versatile
transformations of the product.
Related Results
Dimensions of Accountability: Voices from New Zealand Primary Health Organisations
Dimensions of Accountability: Voices from New Zealand Primary Health Organisations
<p>Cooperative activity necessitates participants acknowledging joint goals, often delegating resources, consequent performance, tailored accountability reporting and feedbac...
3.1 Heck Reactions
3.1 Heck Reactions
AbstractThe arylation of terminal alkenes bearing mesomerically electron-withdrawing groups is the archetypal palladium(0)-catalyzed Heck reaction, also known as the Mizoroki–Heck ...
47.1.2.1.6 Alkyl-Mizoroki–Heck-Type Reactions
47.1.2.1.6 Alkyl-Mizoroki–Heck-Type Reactions
AbstractSubstituted alkenes are basic structural motifs in a large number of organic molecules and their synthesis has received continuous attention from synthetic chemists. One of...
Improved Phos‐tag SDS‐PAGE under neutral pH conditions for advanced protein phosphorylation profiling
Improved Phos‐tag SDS‐PAGE under neutral pH conditions for advanced protein phosphorylation profiling
AbstractWe describe an improved Phos‐tag SDS‐PAGE (Zn2+–Phos‐tag SDS‐PAGE) using a dizinc(II) complex of Phos‐tag acrylamide in conjunction with a Bis‐tris‐buffered neutral‐pH gel ...
3.1.2.2 Formation of Heterocycles
3.1.2.2 Formation of Heterocycles
AbstractThe formation of heterocycles through the Heck cross-coupling reaction has been studied extensively as it allows potential efficient access to a large variety of compounds....
On Homogeneous Gold/Palladium Catalytic Systems
On Homogeneous Gold/Palladium Catalytic Systems
AbstractTwo substrates containing an aryl iodide and an allenoate ester were prepared and the gold‐induced cycloisomerisation to vinylgold(I) species and their proto‐deauration as ...
Recent advances in enantioselective reactions of terminal unactivated alkenes
Recent advances in enantioselective reactions of terminal unactivated alkenes
α-Olefins as aliphatic terminal alkenes could be obtained easily from
numerous contemporary synthetic reactions as well as petrochemical
industry, and also found in natural product...
The Hydroformylation Reaction
The Hydroformylation Reaction
AbstractThe reaction of 1‐alkenes with carbon monoxide and hydrogen in the presence of a catalyst gives the corresponding homologous aldehydes. The discovery of this reaction was m...