ASSA13-10-21 Effect of Bleeding on Hospitalised Mortality in Acute Myocardial Infarction Patients Aged 80 and Over

Objective To detect the effect of bleeding on hospitalised acute myocardial infarction (AMI) mortality in patients aged 80 and over. Methods Life-threatening bleeding and major or minor bleeding is defined according to TIMI criteria. In a cohort of AMI patients aged ≥80 years from 2003 to 2012 at CCU department in fuxing hospital, the bleeding condition and the effect of bleeding on mortality was evaluated. Results 386 patients presenting with ST segment elevation AMI (STEMI) and non-STEMI were enrolled. A total of 90 patients died among hospital, and bleeding was observed in 45 cases, including 13.3% of TIMI life-threatening bleeding, 15.6% of TIMI major and 71.1% of minor bleeding. 111 cases of bleeding were observed in the survivors, including 11.7% of major bleeding and 88.3% of minor bleeding. The TIMI life-threatening bleeding and major bleeding There was significant difference in bleeding between the two groups, X2 = 16.303, P < 0.001. Binary logistic regression analysis showed major bleeding and life-threatening bleeding was an independent significant predictor associated with mortality among hospital, OR 3.062, P = 0.011, 95% CI: 1.288–7.282. Conclusions Patients aged 80 and over have high bleeding during hospitalisation, major and life-threatening bleeding was an independent significant predictor associated with hospitalised mortality.