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On the Origin of Urocanic Acid in the Horny Layer
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In 4 volunteers samples of skin scrapings taken at various depths on the fore-arms were collected for determination of the urocanic acid, amino-nitrogen, and sodium content. The percentage of urocanic acid in the samples from deeper levels was higher than in the superficial material. The ratio between the amounts of urocanic acid and amino-nitrogen was the same in all layers. It is therefore concluded that the urocanic acid in the human stratum corneum is of epidermal origin and is not derived from sweat.
Title: On the Origin of Urocanic Acid in the Horny Layer
Description:
In 4 volunteers samples of skin scrapings taken at various depths on the fore-arms were collected for determination of the urocanic acid, amino-nitrogen, and sodium content.
The percentage of urocanic acid in the samples from deeper levels was higher than in the superficial material.
The ratio between the amounts of urocanic acid and amino-nitrogen was the same in all layers.
It is therefore concluded that the urocanic acid in the human stratum corneum is of epidermal origin and is not derived from sweat.
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