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Triamcinolone
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Abstract
Triamcinolone is a fluorinated prednisolone derivative with less mineralocorticoid activity than prednisolone. Considered an intermediate-duration glucocorticoid, triamcinolone has both clinical and veterinary usage as an anti inflammatory glucocorticoid (2,6). The white crystals of triamcinolone have a MP of 269°-271°C (6).
Oral or injectable triamcinolone is used to treat many allergic or inflammatory diseases. Triamcinolone is given intranasally for seasonal and perennial allergic rhinitis and topically to relieve inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Aerosolized triamcinolone is used to treat children and adults with asthma.
Following intranasal triamcinolone, headache occurs in about 18% of patients. A range of adverse effects, including nasal irritation, dry mucous membranes, congestion, throat discomfort, sneezing, and epistaxis can be experienced. Inhalation-specific side effects include hoarseness, throat irritation, and dry mouth. Adrenal suppression may occur after use of triamcinolone, especially in high doses or for a prolonged time (6).
Title: Triamcinolone
Description:
Abstract
Triamcinolone is a fluorinated prednisolone derivative with less mineralocorticoid activity than prednisolone.
Considered an intermediate-duration glucocorticoid, triamcinolone has both clinical and veterinary usage as an anti inflammatory glucocorticoid (2,6).
The white crystals of triamcinolone have a MP of 269°-271°C (6).
Oral or injectable triamcinolone is used to treat many allergic or inflammatory diseases.
Triamcinolone is given intranasally for seasonal and perennial allergic rhinitis and topically to relieve inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Aerosolized triamcinolone is used to treat children and adults with asthma.
Following intranasal triamcinolone, headache occurs in about 18% of patients.
A range of adverse effects, including nasal irritation, dry mucous membranes, congestion, throat discomfort, sneezing, and epistaxis can be experienced.
Inhalation-specific side effects include hoarseness, throat irritation, and dry mouth.
Adrenal suppression may occur after use of triamcinolone, especially in high doses or for a prolonged time (6).
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Abstract
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