Overview on Osmotic Drug Delivery System

The aim of the current review is to elaborate on the osmotic drug delivery system for controlled release of drugs. The oral route is the most conventional and acceptable route of drug administration. Osmotic Drug Delivery Systems (ODDS) are gaining importance as these systems deliver the drug at specific times as per the functional needs of the disease, resulting in improved patient therapeutic efficacy and compliance. The osmotic drug delivery system serves as a tool for controlling drug release in these conditions and avoiding frequent administration, which is necessary for the treatment of chronic diseases that require repeated dose administration. To control drug delivery, they employ the osmotic pressure theory. To a significant extent, the drug's release is independent of GIT functional variables. This review paper highlights the osmotic drug delivery system's structure, numerous unique osmotic technologies, various factors that affect the drug's release from the system and the status of currently sold and in-progress products that use the system. Keywords Plasma concentration; Controlled drug delivery; Osmotic drug delivery; Osmosis; Osmotic pressure