Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Intracellular Calcium Response to Oxytocin in Uterine Smooth Muscle Cells From Patients With Uterine Atony
View through CrossRef
(Anesth Analg. 2025;140(2):491–493. DOI: 10.1213/ANE.0000000000007240)
Postpartum hemorrhage (PPH) is a leading cause of maternal death globally, with uterine atony being responsible for about 80% of these cases. In the United States, it is the second-highest pregnancy-related cause of death. Uterine atony occurs when the uterus fails to contract properly after the delivery of the placenta, and it remains a challenge to study due to the lack of effective in vivo or in vitro models. Cytosolic calcium (Ca2+) plays a critical role in muscle contraction, including uterine smooth muscle, and its response to stimuli such as oxytocin is central to understanding uterine atony. This study aimed to investigate whether oxytocin-induced calcium changes in uterine smooth muscle cells (USMCs) could provide insight into uterine atony.
Ovid Technologies (Wolters Kluwer Health)
Title: Intracellular Calcium Response to Oxytocin in Uterine Smooth Muscle Cells From Patients With Uterine Atony
Description:
(Anesth Analg.
2025;140(2):491–493.
DOI: 10.
1213/ANE.
0000000000007240)
Postpartum hemorrhage (PPH) is a leading cause of maternal death globally, with uterine atony being responsible for about 80% of these cases.
In the United States, it is the second-highest pregnancy-related cause of death.
Uterine atony occurs when the uterus fails to contract properly after the delivery of the placenta, and it remains a challenge to study due to the lack of effective in vivo or in vitro models.
Cytosolic calcium (Ca2+) plays a critical role in muscle contraction, including uterine smooth muscle, and its response to stimuli such as oxytocin is central to understanding uterine atony.
This study aimed to investigate whether oxytocin-induced calcium changes in uterine smooth muscle cells (USMCs) could provide insight into uterine atony.
Related Results
Comparison of the Effectiveness of 5 IU Oxytocin Bolus and 20 IU Infusion on Uterine Contraction and Hemodynamic Response in Caesarean Section
Comparison of the Effectiveness of 5 IU Oxytocin Bolus and 20 IU Infusion on Uterine Contraction and Hemodynamic Response in Caesarean Section
Uterine atonic can result in postpartum hemorrhage, gravid hysterectomy andmaternal mortality. Oxytocin is the most commonly used agent for the preventionand treatment of atonic ut...
024 Quiescent Wakefulness: Characterising the Impact of Oxytocin on Sleep-Wake Behaviour in Male and Female Rats
024 Quiescent Wakefulness: Characterising the Impact of Oxytocin on Sleep-Wake Behaviour in Male and Female Rats
Abstract
Introduction
Oxytocin is a versatile hypothalamic neuropeptide involved in diverse neurobehavioural processes. Since ox...
Oxytocin Released within the Supraoptic Nucleus of the Rat Brain by Positive Feedback Action is Involved in Parturition‐Related Events
Oxytocin Released within the Supraoptic Nucleus of the Rat Brain by Positive Feedback Action is Involved in Parturition‐Related Events
Oxytocin is released within the supraoptic nucleus during parturition and suckling. During suckling, such release is important in positive feedback stimulation of oxytocin neurons....
Poster 247: Muscle ERRγ Overexpression Mitigates the Muscle Atrophy after ACL injury
Poster 247: Muscle ERRγ Overexpression Mitigates the Muscle Atrophy after ACL injury
Objectives:
Anterior cruciate ligament (ACL) reconstruction is the 6th most common orthopedic procedure performed in the United States (1,2). There is substanti...
Association of Cigarette Smoking Exposure in Pregnant patients and Uterine Atony
Association of Cigarette Smoking Exposure in Pregnant patients and Uterine Atony
Background: Uterine atony, is one of the life-threatening emergency obstetrics complications that may be affected by
vitamin D deficiency and cigarette smoking.
Objective: To study...
British Food Journal Volume 45 Issue 9 1943
British Food Journal Volume 45 Issue 9 1943
I now pass on to an aspect of calcium metabolism which is more topical, but probably more controversial. I refer to the incidence of calcium deficiency. By what means can we determ...
Relationship Between Preeclampsia and Anemia with The Risk of Uterine Atony
Relationship Between Preeclampsia and Anemia with The Risk of Uterine Atony
Preeclampsia-eclampsia causes changes in vital organs, one of which is endothelial cell dysfunction. Preeclampsia carries a risk of uterine atony because when the mother experience...
PENGARUH PIJAT OKSITOSIN TERHADAP KELANCARAN PRODUKSI ASI PADA IBU MENYUSUI DI KELURAHAN YUKUM JAYA KEC. TERBANGGI BESAR KAB. LAMPUNG TENGAH
PENGARUH PIJAT OKSITOSIN TERHADAP KELANCARAN PRODUKSI ASI PADA IBU MENYUSUI DI KELURAHAN YUKUM JAYA KEC. TERBANGGI BESAR KAB. LAMPUNG TENGAH
Breast milk is a single food that can meet the needs of babies up to 6 months. Breastfeeding is the ideal feeding for the growth and development of infants. The importance of breas...