Prenatal Diagnosis of Jarcho-Levin Syndrome in the First Trimester

<i>Introduction:</i> Jarcho-Levin syndrome is a congenital segmental costo-vertebral deformation with multiple vertebral and numerical or structural rib abnormalities resulting in the ‘crab-like’ aspect of the chest. We desribe an ultrasound antenatal diagnosis of the Jarcho-Levin syndrome with spina bifida during the first trimester of pregnancy. <i>Case Report:</i> Prenatal ultrasonography showed shortened spine with marked kyphoscoliosis and spina bifida. <i>Conclusion:</i> If a prenatal diagnosis of Jarcho-Levin syndrome is made before viability, the choice of pregnancy termination should be offered to the parents.