Sensitization to fragrance materials in Indonesian cosmetics

2 different groups of patients were patch tested with 2 test series (A arid B) containing extracts of fragrance raw materials. traditionally used in Indonesian cosmetics, Series A consisted of diluted extracts of commercially available Indonesian fragrances. Series B consisted of extracts prepared in mir department from corresponding indigenous flowers and fruits. Group I consisted of 32 patients positive lo fragrance‐mix, of whom S (25%) had positive tests to 1 or more of the different extracts of fragrance raw materials. Reactions were observed to extracts of: Rosa hybrida Hort (7); Canangium odoratum Baill (5); Citrus aurantifolia Swingle(4); Jasminum sumbac Ait (2). 6 of the S patients, had reactions to 1 or more of the components of fragrance‐mix: oakmoss (3); cinnamic alcohol (2). isoeugenol (1); cinnamic aldehyde (1) and geraniol (1). Group 2 consisted of 1 59 patients patch tested on suspicion of contact dermatitis, who were fragrance‐mix negative. Only 2 (1.2%) had a positive patch test to the extracts of fragrance raw materials. Specimens taken (as is) from the flowers and citrus fruits (being the basic sources of the fragrance raw materials) were less antigenic. The use of additional test series in Indonesia to detect allergy to traditional cosmetics and perfumes merits further investigation.