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MALIGNANT PLEURAL MESOTHELIOMA.
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El mesotelioma es un tumor raro, agresivo y de mal pronóstico. La supervivencia a los 5 años no supera el 10% en algunas series. A día de hoy, el asbesto es el principal factor de riesgo para su desarrollo. Es un tumor heterogéneo debido a las alteraciones en la metilación del ADN. La clínica es inespecífica, debutan con derrame pleural, dolor, disnea, tos y síndrome constitucional. Se realiza inicialmente una radiografía de tórax en la que se encontrará engrosamiento pleural, derrame y pérdida de volumen. En el TAC se podrá apreciar engrosamiento pleural y derrame en algunos casos. Los pacientes con derrame pleural podrán beneficiarse de la toracocentesis, que será diagnóstica en el 32% de las ocasiones. En caso de derrame pleural recidivante, dentro del manejo paliativo, podría valorarse la colocación de drenaje pleural tunelizado de cara al alivio sintomático en estos pacientes
Title: MALIGNANT PLEURAL MESOTHELIOMA.
Description:
El mesotelioma es un tumor raro, agresivo y de mal pronóstico.
La supervivencia a los 5 años no supera el 10% en algunas series.
A día de hoy, el asbesto es el principal factor de riesgo para su desarrollo.
Es un tumor heterogéneo debido a las alteraciones en la metilación del ADN.
La clínica es inespecífica, debutan con derrame pleural, dolor, disnea, tos y síndrome constitucional.
Se realiza inicialmente una radiografía de tórax en la que se encontrará engrosamiento pleural, derrame y pérdida de volumen.
En el TAC se podrá apreciar engrosamiento pleural y derrame en algunos casos.
Los pacientes con derrame pleural podrán beneficiarse de la toracocentesis, que será diagnóstica en el 32% de las ocasiones.
En caso de derrame pleural recidivante, dentro del manejo paliativo, podría valorarse la colocación de drenaje pleural tunelizado de cara al alivio sintomático en estos pacientes.
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