In-vivo and In- vitro Antidiabetic potential of Musa balbisiana colla and its different parts

The present study was performed to determine the antidiabetic activity of Musa balbisiana colla seed, peel, pulp and flower extract. The methanolic extract of Musa balbisiana was evaluated for its inhibition activity on α- amylase and α- glucosidase enzymes. The methanolic seed extract exhibited highest inhibition against α- amylase and α- glucosidase with IC50 values of 121±0.40 and 101±0.53. The effect of Musa balbisiana pulp, seed and flower on fasting blood glucose level in streptozotocin (STZ) induced diabetic rat was studied. On prolong administration of seed extract, it was seen that effectively reduced the blood glucose level and has effective slight increase in body weight. Thus the result indicates that extract of Musa balbisiana colla seed and flower posses potent antidiabetic property.