TO COMPARE THE EFFICACY OF ORAL ACETAZOLAMIDE VS EPLERENONE IN PATIENTS OF CENTRAL SEROUS CHORIORETINOPATHY

Serous detachment of the neurosensory retina due to one or more focal retinal pigment epithelium (RPE) lesions is a characteristic of the retinal disorder known as central serous chorioretinopathy (CSCR). In 1866, Von Graefe first recognized central serous chorioretinopathy (CSCR) as relapsing central luetic retinitis.Males are more likely than females to develop CSCR, which is most common in midlife. CSCR is regarded as the fourth most frequent non-surgical retinopathy and a common cause of visual impairment in individuals of working age, behind diabetic retinopathy, age-related macular degeneration, and retinal vein occlusion. Major symptoms of CSCR includesImpaired vision, Usually Unilateral,Concomitant micropsia and Metamorphopsia, which the patient normally perceives as a dark area in the center of the visual field. Pathophysiology Of CSCR-Guyer et al. suggested ICG-video angiography (ICG-V) as a potential model for the pathophysiology of CSCR. They found that while FA did not exhibit diffuse hyperpermeability around active leakage sites, ICG-V did. They therefore concluded that hyperpermeability existed at the choroid level rather than the retinal pigment epithelium (RPE) level.Choroidal hyperpermeability is hypothesized to be the source of serous detachments of the RPE, which can cause the RPE to tear or decompensate.