Mucosal Vaccines for Gastrointestinal Infections

 Infections of the digestive system are responsible for many illnesses and deaths in all ages worldwide. Conventional ways of producing vaccines have proven inefficient at fighting these diseases, mainly because they cannot instigate mucosal defenses, which are vital in protecting the entry points against pathogens. Mucosal vaccines, meant to stimulate immune reactions on the mucus membranes, may be more effective in preventing gastrointestinal infections. The chapter gives a general idea of the current state of mucosal vaccines in gastrointestinal infections. First, we will explore the different forms of gastrointestinal infections, including bacterial, viral, and parasitic, identifying their prevalence and how they impact public health. Furthermore, we consider conventional vaccine strategies such as restricted elicitation of mucosal immune response and antibiotic resistance strains. The major role of mucosal immunity against gastrointestinal pathogens will be discussed. The chapter gives a general idea of the current state of mucosal vaccines in gastrointestinal infections. First, we will explore the different forms of gastrointestinal infections, including bacterial, viral, and parasitic, identifying their prevalence and how they impact public health. Furthermore, we consider conventional vaccine strategies such as restricted elicitation of mucosal immune response and antibiotic resistance strains. The major role of mucosal immunity against gastrointestinal pathogens will be discussed. Moreover, we have dealt with problems such as vaccine manufacture and regulation by emphasizing the ongoing research in this area. To finish, they are a better way to prevent gastrointestinal infections by using the body’s defense mechanisms. Continuous investments in mucosal vaccine development and fresh ideas are highly needed to effectively address the worldwide burden of gastrointestinal ailments.