The Outcome of Self-expandable Metallic Stent for Malignant Tracheobronchial Stenosis Following Esophageal Stenting

Abstract Background: Tracheobronchial stenosis following esophageal stenting is rare. We aim to explore the outcome of SEMS for malignant tracheobronchial stenosis following esophageal stenting.Methods: Clinical and imaging data of 20 patients (12 males, 8 females) with malignant tracheobronchial stenosis following esophageal stenting from Jan 2014 to Jan 2019 were retrospectively analyzed. Data of the location of tracheobronchial stenosis, stent types, Borg score before and after airway stenting, indication of esophageal stent placement, interval between double stents placement and survival time after airway stenting were collected.Results: A total of 20 stents (13 Y-shaped stents, 7 tube stents) were successful placement in all patients without procedure-related complications happened. Seven of them are tracheal stenosis, 5 carina stenosis and 8 multiple stenosis. The mean Borg score before and after airway stenting are 6.6±1.1 and 1±0.5 (P<0.001). The interval between double stents placement in patients who received chemoradiotherapy is 146.29±106.77 days, while in palliation therapy is 41.83±146.29 days(P<0.05). The mean survival time after esophageal stenting in patients who received chemoradiotherapy is 232.79 ±97.71 days, while in palliation therapy is 163 ± 113.50 days(P=0.230). The mean survival time after airway stenting in patients who received chemoradiotherapy is 86.5 ±52.47 days, while in palliation therapy is 121.17 ± 113.48 days(P=0.461).Conclusion: The application of SEMS in malignant tracheobronchial stenosis following esophageal stenting is safe and effective. Chemoradiotherapy is a factor affect the interval between double stents placement.