Prevalence and Susceptibility Pattern of Vibrio Cholerae Among Patients Attending North East Medical College Hospital, Sylhet

Abstract Vibrio cholerae is a common bacterial enteropathogen causing acute diarroheal disease in the developing world. Extensive & injudicious use of antimicrobials has led to the emergence of Vibrio cholerae that are resistant to several antibiotics. A cross-sectional laboratory-based experimental study was conducted on the stool samples of One hundred and Ninety (190) patients diarrhoeic attending different out-patient departments of North East Medical College Hospital to determine the presence of Vibrio cholerae and their antibiotic susceptibility pattern from January 2017 to December 2017. Patients’ age ranged from 2 months to 65 years. Stool samples were collected & tested for Vibrio cholerae using conventional stool culture in the Microbiology laboratory of North East Medical College Hospital. Forty three (43) out of one hundred and ninety (190) samples had shown the growth of Vibrio cholerae (22.63%). The isolates were sensitive to Ciprofloxacin, Ceftriaxone, Co-trimoxazole, Meropenam, Imipenam, Tetracycline, Amoxycyline. No bacterial isolate was found resistant to all antibiotics used in the antibiotic panel. Though the obtained study result revealed that some of the antibiotics used to treat Cholera are still effective but antibiotic resistance often leads to therapeutic failure of empirical therapy. To minimize this problem, antibiotic should be used rationally & susceptibility testing should be encouraged on routine basis. Key Words: Choleare, Stool, Vibrio cholerae, antibiotic susceptibility.