Azadirachta Indica:Indian Neem,A Natural Killer of Microorganisms

Abstract-Medicinal Plants are always of immense vital component for pharmaceutical word. Azadirachta indica, commonly known as neem, has attracted worldwide prominence in recent years owing to its wide range of medicinal properties. Neem is a medicinal plant which is always at top from ancient world to modern world. The importance of the neem tree has been recognized by the US National Academy of Sciences, which published a report in 1992 entitled 'Neem- a tree for solving global problems'. Various parts of neem are sources for mankind to treat many severe diseases. More than 140 compounds have been isolated from different parts of neem. All parts of the neem tree- leaves, flowers, seeds, fruits, roots and bark have been used traditionally for the treatment of inflammation, infections, fever, skin diseases and dental disorders. Neem leafanditsconstituentshavebeendemonstrated to exhibit immunomodulatory, anti-inflammatory,antihyperglycaemic,antiulcer,antimalarial,antifungal,antibacterial,antiviral,antioxidant,antimutagenicandanticarcinogenicproperties. Keeping these points in view the present study is aimed to study antimicrobial activity of plant extracts prepared from leaves of neem plant against Klebsiella pneumoniae,Pseudomonasaeruginosa,Bacillus subtilis, Staphylococcus aureus and Escherichia coli. There is a significant antimicrobial activity observed by neem leave extract against these microbial strains.