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Dynamic Thiol/Disulphide Homeostasis in Patients With Fibromyalgia
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Objectives: This study aims to investigate dynamic thiol/disulphide homeostasis in patients with fibromyalgia syndrome (FMS).
Patients and methods: Fifty female patients with FMS (mean age 40.5±7.2 years; range 21 to 55 years) and 40 healthy female controls (mean age 39±9.4 years, range 22 to 55 years) were included in the study. Pain visual analog scale, tender points, Fibromyalgia Impact Questionnaire, and Beck Depression Inventory were evaluated. Age, body mass index (BMI), and symptom durations were also recorded. Native thiol, disulphide and total thiol levels were measured with a novel automated method.
Results: Serum disulphide levels were 14.7±3.4 μmol/L and 22.2±3.6 μmol/L in the FMS and control groups, respectively (p
Title: Dynamic Thiol/Disulphide Homeostasis in Patients With Fibromyalgia
Description:
Objectives: This study aims to investigate dynamic thiol/disulphide homeostasis in patients with fibromyalgia syndrome (FMS).
Patients and methods: Fifty female patients with FMS (mean age 40.
5±7.
2 years; range 21 to 55 years) and 40 healthy female controls (mean age 39±9.
4 years, range 22 to 55 years) were included in the study.
Pain visual analog scale, tender points, Fibromyalgia Impact Questionnaire, and Beck Depression Inventory were evaluated.
Age, body mass index (BMI), and symptom durations were also recorded.
Native thiol, disulphide and total thiol levels were measured with a novel automated method.
Results: Serum disulphide levels were 14.
7±3.
4 μmol/L and 22.
2±3.
6 μmol/L in the FMS and control groups, respectively (p.
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