Supplementary Figures 1-6 from HDAC3 Is Required for XPC Recruitment and Nucleotide Excision Repair of DNA Damage Induced by UV Irradiation

<p>Supplementary Figure S1. Depletion of HDAC3 increases UV sensitivity and delays CPD removal. Supplementary Figure S2. HDAC3 does not interact with NER factors in the presence or absence UV irradiation. Supplementary Figure S3. HDAC3 facilitates XPC and TFIIH recruitment in U2OS cells. Supplementary Figure S4. Most XPC localizes to chromatin in the absence of DNA damage. Supplementary Figure S5. Depletion of HDAC3 induces continuous checkpoint activation in response to DNA damage. Supplementary Figure S6. Representative immunostaining of cells after local UV irradiation in Figure 6B.</p>