Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
DOES INTERFERON (IFN)S EXIST IN CRUSTACEA?
View through CrossRef
The wide exploration of interferon (IFN)s in vertebrates for medical purposes has attracted researchers to investigate the existence of a similar role of interferon in other organisms such as invertebrates, including insects, and crustacea. A review of the literature indicates that there is no evidence of interferon existing either in insects such as D. melanogaster and A. gambiae which have had their genomes fully sequenced or in crustacea. However, a nonspecific antiviral state in crustacean, such as P. monodon can be efficiently triggered by both dsRNA and siRNA. The evidence suggests that anonymous cytokines, similar to interferon and not identical to any vertebrate IFNs, related to antiviral protection, do exist in crustacea. However, how widely spread of interferon immune response inducer or interferon-like molecules in this group is an important issue that remains to be explored.
Agency for Marine and Fisheries Research and Development
Title: DOES INTERFERON (IFN)S EXIST IN CRUSTACEA?
Description:
The wide exploration of interferon (IFN)s in vertebrates for medical purposes has attracted researchers to investigate the existence of a similar role of interferon in other organisms such as invertebrates, including insects, and crustacea.
A review of the literature indicates that there is no evidence of interferon existing either in insects such as D.
melanogaster and A.
gambiae which have had their genomes fully sequenced or in crustacea.
However, a nonspecific antiviral state in crustacean, such as P.
monodon can be efficiently triggered by both dsRNA and siRNA.
The evidence suggests that anonymous cytokines, similar to interferon and not identical to any vertebrate IFNs, related to antiviral protection, do exist in crustacea.
However, how widely spread of interferon immune response inducer or interferon-like molecules in this group is an important issue that remains to be explored.
Related Results
Long-Term Interferon-α Treatment in Essential Thrombocythemia
Long-Term Interferon-α Treatment in Essential Thrombocythemia
Abstract
Background: Essential thrombocythemia (ET) is a chronic myeloid stem cell disorder characterized by an uncontrolled production of platelets....
Type I interferon signaling promotes early innate control of
Borrelia burgdorferi
infection
Type I interferon signaling promotes early innate control of
Borrelia burgdorferi
infection
ABSTRACT
Borrelia burgdorferi
, the causative agent of Lyme disease, elicits a robust type I interferon (IFN-I) response that h...
The Impact of IL28B Gene Polymorphisms on Drug Responses
The Impact of IL28B Gene Polymorphisms on Drug Responses
To achieve high therapeutic efficacy in the patient, information on pharmacokinetics, pharmacodynamics, and pharmacogenetics is required. With the development of science and techno...
P087 IFN-γ-Induced Intestinal Epithelial Cell Type-Specific Cytotoxic Responses of Human Enteroids: PANoptosis and The Protective Role of Selective JAK1 Inhibitors
P087 IFN-γ-Induced Intestinal Epithelial Cell Type-Specific Cytotoxic Responses of Human Enteroids: PANoptosis and The Protective Role of Selective JAK1 Inhibitors
Abstract
Background
Interferon-gamma (IFN-γ) plays an important role in the development of intestinal injury and inflammatory bo...
Does the interferon-lambda rather than the interferon-alpha pathway determine the outcome of hepatitis C virus infection?
Does the interferon-lambda rather than the interferon-alpha pathway determine the outcome of hepatitis C virus infection?
Abstract
The molecular mechanisms that link IFN-λ3 genotypes to differential induction of interferon (IFN)-stimulated genes (ISGs) in the liver of patients with chronic...
P11.01 TMZ-LEV- IFN cocktail regimen significantly inhibited the growth of glioma
P11.01 TMZ-LEV- IFN cocktail regimen significantly inhibited the growth of glioma
Abstract
BACKGROUND
TMZ, is the first line chemotherapeutic drug for glioma, and drug resistance is one of the most important re...
A Novel Cell-based In vitro Assay for Antiviral Activity of Interferons α, β, and γ by qPCR of MxA Gene Expression
A Novel Cell-based In vitro Assay for Antiviral Activity of Interferons α, β, and γ by qPCR of MxA Gene Expression
Background:Human MxA gene is related to the class of interferon (IFN)-stimulated genes (ISGs) that plays a role in antiviral resistance.Objective:Implementation of standard curves ...
Interferon response heterogeneity: activation of a pro-inflammatory response by interferon α and β. A possible basis for diverse responses to interferon β in MS
Interferon response heterogeneity: activation of a pro-inflammatory response by interferon α and β. A possible basis for diverse responses to interferon β in MS
Abstract
Interferon γ (IFN-γ) stimulates the (pro-inflammatory) type II interferon receptor and is known to exacerbate multiple sclerosis (MS). In contrast, IFN-α an...