Experience with prepectoral implant-based reconstruction for breast cancer

Prepectoral implant-based simultaneous breast reconstruction is now employed more often and demonstrates good long-term outcomes with good quality of life after breast cancer (BC) surgery. We share our experience with reconstructive surgeries performed in 308 women diagnosed with BC by prepectoral implant placement. Polyurethane-coated implants were used in 50%, textured implants in 42.2%, and tissue expanders later replaced by textured implants in 7.8%. Prepectoral implant-based breast reconstruction was most commonly (74.5%) performed in women with early disease (stage 0-IIa). 150 women (48.7%) received chemotherapy after surgery. 40 women (12.9%) received radiotherapy (60% were women with polyurethane implants and 40% were women with textured implants). Radiotherapy was performed in 12 women (3.8%) with tissue expanders. In some women, complications occurred in the setting of ongoing radiotherapy and/or chemotherapy, which illustrates the need for careful patient selection for this surgical intervention. Improving surgical techniques and methods for preventing complications allows more active and effective introduction of prepectoral implant-based breast reconstruction. KEYWORDS: prepectoral reconstruction, implant-based breast reconstruction, breast cancer, tissue expander, textured implant, polyurethane implant. FOR CITATION: Khodorovich O.S., Solodkiy V.A., Kalinina-Masri A.A., Tashchyan A.A., Sherstneva T.V., Kleshneva V.O., Kanakhina L.B. Experience with prepectoral implant-based reconstruction for breast cancer. Russian Medical Inquiry. 2023;7(6):366–371 (in Russ.). DOI: 10.32364/2587-6821-2023-7-6-5.