Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Genome-Wide Association Study of Multi-Traits in Common Bean (Phaseolus Vulgaris L.)
View through CrossRef
Abstract
Background: Micronutrient deficiencies caused by lack of Iron (Fe), Zinc (Zn) and Vitamin A have negative effects on human health worldwide. Even though common bean meets Fe and Zn deficiencies based on recommended dietary allowances, the cooking time remains an important challenge. Understanding the genome organization, the loci and genes localization controlling multiple traits is crucial for developing enhanced micronutrient content and improved common bean with short cooking time. Results: In this study, GWAS method was used to determine SNPs associated with four traits studied, including water uptake, cooking time, Fe and Zn concentration level, using ~5,000 SNPs for a panel of 206 genotypes. By the analysis of population structure, 206 common bean genotypes were formed in three groups, the Mesoamerican gene pool, the Andean gene pool, and the admixture gene pool using the Bayesian method. With the significance levels between p = 2.94 x 10-08 to p = 8.33 x 10-03 and phenotypic variation of 8.26% to 18.19%, total of 10 SNPs was found to be significantly associated with traits on chromosomes Pv03, Pv04 and Pv10. Among of these SNPs, four SNPs were associated with water uptake, another four SNPs with the cooking time, one SNP with Zn concentration and one of less significant SNP associated with Fe concentration. Within the range or nearby the peak of significant SNP, putative loci encoding pectin degradation, cell structure and cellular exchange/transport were identified, suggesting these loci may play important roles in modulating expression of traits.Conclusion: The resultant data in this study contributed on deciphering the molecular mechanisms associated with water uptake, cooking time and micronutrient contents in common bean. The investigation of association between phenotypic and genotypic data has showed that GWAS approach is a powerful tool to dissect genetic architecture of complex traits and cooperate molecular breeding for advanced genotypes with enhanced micronutrients and short cooking time.
Springer Science and Business Media LLC
Title: Genome-Wide Association Study of Multi-Traits in Common Bean (Phaseolus Vulgaris L.)
Description:
Abstract
Background: Micronutrient deficiencies caused by lack of Iron (Fe), Zinc (Zn) and Vitamin A have negative effects on human health worldwide.
Even though common bean meets Fe and Zn deficiencies based on recommended dietary allowances, the cooking time remains an important challenge.
Understanding the genome organization, the loci and genes localization controlling multiple traits is crucial for developing enhanced micronutrient content and improved common bean with short cooking time.
Results: In this study, GWAS method was used to determine SNPs associated with four traits studied, including water uptake, cooking time, Fe and Zn concentration level, using ~5,000 SNPs for a panel of 206 genotypes.
By the analysis of population structure, 206 common bean genotypes were formed in three groups, the Mesoamerican gene pool, the Andean gene pool, and the admixture gene pool using the Bayesian method.
With the significance levels between p = 2.
94 x 10-08 to p = 8.
33 x 10-03 and phenotypic variation of 8.
26% to 18.
19%, total of 10 SNPs was found to be significantly associated with traits on chromosomes Pv03, Pv04 and Pv10.
Among of these SNPs, four SNPs were associated with water uptake, another four SNPs with the cooking time, one SNP with Zn concentration and one of less significant SNP associated with Fe concentration.
Within the range or nearby the peak of significant SNP, putative loci encoding pectin degradation, cell structure and cellular exchange/transport were identified, suggesting these loci may play important roles in modulating expression of traits.
Conclusion: The resultant data in this study contributed on deciphering the molecular mechanisms associated with water uptake, cooking time and micronutrient contents in common bean.
The investigation of association between phenotypic and genotypic data has showed that GWAS approach is a powerful tool to dissect genetic architecture of complex traits and cooperate molecular breeding for advanced genotypes with enhanced micronutrients and short cooking time.
Related Results
Kadar serum 25-hidroksi vitamin D berkorelasi negatif dengan interleukin-17 pada acne vulgaris derajat berat
Kadar serum 25-hidroksi vitamin D berkorelasi negatif dengan interleukin-17 pada acne vulgaris derajat berat
Background: Acne vulgaris is a common skin disease in Indonesia. Inflammation is a key factor in its development. 25-hydroxy vitamin D or 25(OH)D is considered to have antioxidant ...
Organoleptic evaluation of lima bean (phaseolus lunatus), mung bean (vigna radiata) and white bean (phaseolus vulgaris) ice cream
Organoleptic evaluation of lima bean (phaseolus lunatus), mung bean (vigna radiata) and white bean (phaseolus vulgaris) ice cream
This study evaluates the organoleptic properties of ice creams made from lima bean (Phaseolus lunatus), mung bean (Vigna radiata), and white bean (Phaseolus vulgaris). The ice crea...
Hubungan Stress Dan Kebersihan Wajah Terhadap Kejadian Akne Vulgaris Pada Mahasiswa Kedokteran Universitas Malahayati
Hubungan Stress Dan Kebersihan Wajah Terhadap Kejadian Akne Vulgaris Pada Mahasiswa Kedokteran Universitas Malahayati
ABSTRACT: RELATIONSHIP OF STRESS AND FACE CLEANLINESS TO THE EVENT OF VULGARIS IN MEDICAL STUDENTS OF UNIVERSITAS MALAHAYATI Background: Acne vulgaris is a disorder of the sebaceou...
Capturing cold-stress-related sequence diversity from a wild relative of common bean (Phaseolus angustissimus)
Capturing cold-stress-related sequence diversity from a wild relative of common bean (Phaseolus angustissimus)
One restriction to the cultivation of common bean, Phaseolus vulgaris L., is its limited tolerance to low temperatures. In the present study, subtraction suppression hybridization ...
Evaluation of Advanced Common Bean (Phaseolus vulgaris L.) Breeding Lines for Multiple Disease Resistance and Yield in Western Kenya
Evaluation of Advanced Common Bean (Phaseolus vulgaris L.) Breeding Lines for Multiple Disease Resistance and Yield in Western Kenya
Common bean (Phaseolus vulgaris L.) is one of the most important legume crops in the world, grown for economical and nutritional value. However, its productivity is constrained by ...
A diallel cross-based analysis of the genetic basis of pod quality and pod yield in snap bean
A diallel cross-based analysis of the genetic basis of pod quality and pod yield in snap bean
Snap bean (Phaseolus vulgaris L.) is among the leading vegetables in Kenya that is mainly grown for export with the potential to increase household income. There are few programs i...
Are Cervical Ribs Indicators of Childhood Cancer? A Narrative Review
Are Cervical Ribs Indicators of Childhood Cancer? A Narrative Review
Abstract
A cervical rib (CR), also known as a supernumerary or extra rib, is an additional rib that forms above the first rib, resulting from the overgrowth of the transverse proce...
Genotypic variation in response to drought stress is associated with biochemical and transcriptional regulation of ureides metabolism in common bean (Phaseolus vulgaris L.)
Genotypic variation in response to drought stress is associated with biochemical and transcriptional regulation of ureides metabolism in common bean (Phaseolus vulgaris L.)
Ureidic legumes such as common bean (Phaseoulus valgaris L.) plants export nitrogen from the nodules to shoots and leaves as ureides during symbiotic biological nitrogen fixation. ...