Ethno pharmacological Efficiency of Andrographis Paniculata against Tuber Rot Disease of Manihot Esculenta (Cassava)

Cassava is a chief and energy rich carbohydrates  food, which might be the reason many parasitic fungi adhere within the  plant that  causes huge damage to  the crop  during the  post  harvesting stage or  storage  period. In the  present  study, the ethno-based possible eradication of parasitic fungi was highlighted. Andrographis paniculata Burm. f. Nees and Stachytarpheta indica were  chosen  for  its popular  medicinal  values  and  the  phytochemical contents  were  characterized.  Its  potency  showed  an inhibitory effects against tuber  rot  disease causing fungal pathogens viz., Rhizopus sp, Mucor sp., Aspergillus niger, Aspergillus flavus and Fusarium oxysporum in Cassava by disc – diffusion methods. The diameter of the zone of inhibition at various concentrations (2.5, 5, 7.5 and 10 w/v) of leaf extracts  was observed  with the  maximum in  A. paniculata (20mm with 10 w/v conc.) against Fusarium  oxysporum  followed  by A.  niger  (17mm  at  10w/v conc.). The  preliminary  phytochemical screening  of  Andrographis paniculata revealed the presence  of phytoconstituents like alkaloids, flavonoids, phenols, and tannins. In GCMS analysis, Benzene,1,2,3-trimethoxy-5-(2-propenyl)-, Cyclopenta [c] pyran-4-carboxylic acid, 7-methyl-, methyl ester  and 9,12,15- Octadecatrienoic acid, methyl ester,  (Z, Z, Z)- covered the high areas, that might be responsible or can possess the antifungal activity against Tuber root  rot causing fungal pathogens. Furthermore,  extensive studies are recommended  to characterize each compound  in the  crude  extracts  of  A.  paniculata  to  enhance or  to  acclaim  remedy for  various  diseases  in plants. This study reveals the acknowledgement of the medicinal plant A. paniculata for its remarkable organic or eco-friendly fungicide potential against cassava tuber rot diseases.