PERINATAL PATHOLOGY AS A RISK FACTOR FOR THE DEVELOPMENT OF BRONCHIAL ASTHMA IN CHILDREN

The aim of the study: to study the perinatal history of children with bronchial asthma depending on the concomitant neurological symptoms. Material and methods of the study: A total of 103 children with moderate bronchial asthma in remission were examined, with an average age of 7.2±1.2 years. The children were divided into 2 groups: the main group, which included 72 children with bronchial asthma and late consequences of perinatal CNS damage, and a comparison group consisting of 31 children with bronchial asthma without concomitant neurological disorders. Results: Based on the data obtained, it was found that perinatal lesions of the central nervous system significantly affect the further development and course of bronchial asthma in children. A burdened heredity for allergic diseases in patients with bronchial asthma against the background of late consequences of perinatal lesions of the central nervous system (the main group) was significantly less common (30.6%; n=22) than in the comparison group - in 67.7% (n=21) of cases. In the main group, the mothers' pregnancies proceeded with some complications (100% of cases), while in the comparison group, only a quarter of the observations revealed a pathological course of pregnancy in mothers, which is undoubtedly a predisposing factor in the formation of perinatal damage to the central nervous system in the main group. KEY WORDS: bronchial asthma, consequences, perinatal damage, central nervous system, neurological symptoms, perinatal history, risk factors, Apgar scale