Antifungal Activities of Cassia angustifolia Leaf Ethanolic Extract against Various Candida Spp.

Indian senna (Cassia angustifolia) is a perennial shrub belonging to the family Fabaceae. Indian senna contains flavonoids, pinnitolos (polyols), acidic polysaccharides, and mineral substances. It also contains two types of glucosides known as sennosides A and B and other compounds, including myricyl alcohol, anthraquinone derivatives, galactose, arabinose, rhamnose, galacturonic acid, chrysophanic acid, salicylic acid, resin, and mannitol. The antifungal activity of the extract was assessed against fungal strains, including Candida albicans (ATCC10231), Candida parapsilosis, and Candida auris. The result showed that the leaf extract of Cassia angustofolia exhibits significant antifungal activity against all tested fungal strains. After the result, Indian Senna which could be used to develop new drugs for the treatment of resistant fungal infections. Further research and optimum preservation, and flavonoids extraction methods is needed, particularly in the developing world, where senna leaf and flower harvest processing methods are more traditional.