Vaccine Development against Paratuberculosis

Paratuberculosis or Johne’s disease (JD) is a chronic granulomatous enteritis affecting ruminants worldwide. It is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and the rate of prevalence is increasing. Based on high economic impacts and public health concern, vaccine development against paratuberculosis is very essential. There is a lot of research articles about finding the best management approach for eradicating MAP, and also finding an ideal vaccine against the disease. But unfortunately, until now, there is no ideal management approach against the disease because we don’t have any ideal vaccine against it. This mini review discuses about management strategies with the focus on researches about various types of vaccines against JD. Keywords: Mycobacterium avium subsp. paratuberculosis (MAP); Vaccine; Johne’s disease; Paratuberculosis; Control