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Glycosaminoglycans and Urine Flow Rate

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The value of glycosaminoglycans determination in urine has been challenged because the relation between the glycosaminoglycans concentration and other signs of kidney damage is a matter of controversy. It is quite possible that the observed discrepancies could be due to the influence of the urine flow rate, the urine concentration and the time of day on the glycosaminoglycans concentration. Therefore, standardization of the urine sampling time and selection of the most appropriate unit to quantify glycosaminoglycans excretion seem to be essential.
Title: Glycosaminoglycans and Urine Flow Rate
Description:
The value of glycosaminoglycans determination in urine has been challenged because the relation between the glycosaminoglycans concentration and other signs of kidney damage is a matter of controversy.
It is quite possible that the observed discrepancies could be due to the influence of the urine flow rate, the urine concentration and the time of day on the glycosaminoglycans concentration.
Therefore, standardization of the urine sampling time and selection of the most appropriate unit to quantify glycosaminoglycans excretion seem to be essential.

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