Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
THIAZOLE DERIVATIVES AS POTENTIAL ANTIDIABETIC AGENTS
View through CrossRef
Various molecules showing pharmacological activities consist of thiazole as a core structure having heteroatom as sulfur and nitrogen. Thiazole is present in many naturally occurring compounds, along with vitamin B1 and penicillin. Thiazole is used in different biological fields, and it is also known as a wonder nucleus. Thiazole moieties are contained in many new compounds, and hence it is one of the essential areas of research. Diabetes is one of the life-threatening diseases and has become a pandemic presently more than 400 million people are suffering from this and likely to be double by the next ten years. Noncompliance, hypoglycemia, and obesity can be caused by most diabetic drugs. As a result, new antidiabetic drugs with thiazole moieties were synthesized with improved efficacy and minimized side effects. Considering the prominence of the past as well as the latest developments in drugs as an antidiabetic drug having thiazole ring as an antidiabetic drug and its significance, is this described in the present review.
Rasayan Journal of Chemistry
Title: THIAZOLE DERIVATIVES AS POTENTIAL ANTIDIABETIC AGENTS
Description:
Various molecules showing pharmacological activities consist of thiazole as a core structure having heteroatom as sulfur and nitrogen.
Thiazole is present in many naturally occurring compounds, along with vitamin B1 and penicillin.
Thiazole is used in different biological fields, and it is also known as a wonder nucleus.
Thiazole moieties are contained in many new compounds, and hence it is one of the essential areas of research.
Diabetes is one of the life-threatening diseases and has become a pandemic presently more than 400 million people are suffering from this and likely to be double by the next ten years.
Noncompliance, hypoglycemia, and obesity can be caused by most diabetic drugs.
As a result, new antidiabetic drugs with thiazole moieties were synthesized with improved efficacy and minimized side effects.
Considering the prominence of the past as well as the latest developments in drugs as an antidiabetic drug having thiazole ring as an antidiabetic drug and its significance, is this described in the present review.
Related Results
Thiazole-Based Antioxidants: Pioneering a Decade of Therapeutic
Advances
Thiazole-Based Antioxidants: Pioneering a Decade of Therapeutic
Advances
Background::
Thiazole-based compounds have attracted considerable interest due to
their potent antioxidant abilities, which are crucial for combating diseases a...
Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents
Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents
Background:Cancer is second leading disease after cardiovascular disease. Presently, Chemotherapy, Radiotherapy and use of chemicals are some treatments available these days. Thiaz...
Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides
Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides
AbstractThis research reports a novel method for synthesizing new thiazole thioglycosides. This series of thiazole thioglycosides were designed by the reaction of potassium cyanoca...
Thiazole Derivatives as Modulators of GluA2 AMPA Receptors: Potent Allosteric Effects and Neuroprotective Potential
Thiazole Derivatives as Modulators of GluA2 AMPA Receptors: Potent Allosteric Effects and Neuroprotective Potential
Thiazole carboxamide derivatives were synthesized in this investigation, with a subsequent examination of their impact on GluA2 AMPA receptors. The synthesized compounds, namely MM...
Synthesis, Characterization, and Antioxidant Activity Evaluation of New N-Methyl Substituted Thiazole-Derived Polyphenolic Compounds
Synthesis, Characterization, and Antioxidant Activity Evaluation of New N-Methyl Substituted Thiazole-Derived Polyphenolic Compounds
Reactive oxygen species play a significant role in various pathological conditions, driving the need for novel, potent antioxidants. While polyphenols are known for their antioxida...
Pharmacological screening of synthetic piperidine derivatives
Pharmacological screening of synthetic piperidine derivatives
Piperidine derivatives are essential heterocyclic compounds that have beneficial roles in the medical and commercial sector. They can be isolated from plant material and can be che...
Synthesis and Biological Properties of New Piperidine Substituted Benzothiazole Derivatives
Synthesis and Biological Properties of New Piperidine Substituted Benzothiazole Derivatives
In present work, ethyl 2-aminobenzo[d]thiazole-6-carboxylate was reacted to piperidine using copper(II) bromide to get ethyl 2-(piperidin-1-yl)benzo[d]thiazole-6-carboxylate. The r...
Research Progress of Diterpenoids with Potential Antidiabetic Activity
Research Progress of Diterpenoids with Potential Antidiabetic Activity
Introduction:
Diabetes mellitus has become a global epidemic. Diterpenoids have complex
and variable structures and are widely distributed in nature. They play a crucial role in di...