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Determinants of Risk for Developing Invasive Mole and Choriocarcinoma Following Hydatidiform Mole
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AbstractIn Aichi prefecture, Japan, 4, 547 hydatidiform moles were registered from 1962 to 1977. Among these hydatidiform moles, 94 choriocarcinomas, 377 invasive moles and 4 undetermined cases occurred until April 1985. In this paper, the high risk factors for post‐molar trophoblastic disease were studied.The results were:
The frequency of mole was one per 349.7 deliveries in Aichi, Japan.
89.8% of invasive moles were diagnosed by the end of the third month after molar evacuation, whereas 42% of choriocarcinomas were found by the end of the 1st year. The necessity of at least 4 years of supervision and follow up was emphasized.
Increased age (>40), the patient's blood type (AB) and the husband's blood type (B) were high risk factors for post‐molar trophoblastic disease, whereas multi‐parity and Rh‐d factor were suggested to lower the risk.
Title: Determinants of Risk for Developing Invasive Mole and Choriocarcinoma Following Hydatidiform Mole
Description:
AbstractIn Aichi prefecture, Japan, 4, 547 hydatidiform moles were registered from 1962 to 1977.
Among these hydatidiform moles, 94 choriocarcinomas, 377 invasive moles and 4 undetermined cases occurred until April 1985.
In this paper, the high risk factors for post‐molar trophoblastic disease were studied.
The results were:
The frequency of mole was one per 349.
7 deliveries in Aichi, Japan.
89.
8% of invasive moles were diagnosed by the end of the third month after molar evacuation, whereas 42% of choriocarcinomas were found by the end of the 1st year.
The necessity of at least 4 years of supervision and follow up was emphasized.
Increased age (>40), the patient's blood type (AB) and the husband's blood type (B) were high risk factors for post‐molar trophoblastic disease, whereas multi‐parity and Rh‐d factor were suggested to lower the risk.
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