Antioxidant Potential and Phytochemical Screening of Mrudweekadi Kashayam – An analytical study

Introduction: The antioxidant potential of herbal formulations is gaining significant attention due to their potential therapeutic benefits in combating oxidative stress-related diseases. Mrudweekadi Kashayam, a traditional polyherbal formulation, is used in Ayurvedic medicine for various health benefits. This study aims to evaluate the antioxidant potential and phytochemical composition of Mrudweekadi Kashayam. Methods: The formulation was procured from GMP certified pharmacy. The antioxidant potential was assessed using standard in vitro assays, including DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging, FRAP (ferric reducing antioxidant power) assays. The phytochemical screening was performed in the Central Research Facility of KAHER’s Shri BMK Ayurveda Mahavidyalaya, Shahapur, Belagavi.to identify the presence of bioactive compounds such as alkaloids, flavonoids, tannins, phenols, and saponins. Results: Mrudweekadi Kashayam demonstrated significant antioxidant activity in all the assays, with the highest activity observed in the DPPH assay. The phytochemical screening revealed the presence of a rich profile of bioactive compounds, including alkaloids, flavonoids, tannins, phenols, and saponins. These compounds are known for their antioxidant properties and contribute to the overall antioxidant potential of the formulation. Discussion: The findings indicate that Mrudweekadi Kashayam possesses potent antioxidant activity, which may be attributed to its diverse phytochemical composition. The presence of multiple bioactive compounds suggests a synergistic effect, enhancing the formulation's ability to neutralize free radicals and mitigate oxidative stress. Conclusion: Mrudweekadi Kashayam exhibits significant antioxidant potential and contains a variety of bioactive phytochemicals. This formulation may serve as a promising candidate for further research and development in the treatment and prevention of oxidative stress-related diseases. Keywords:  Mrudweekadi kashayam, Antioxident, DPPH, FRAP, Phytochemicals, Analytical study