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Immunodepression by Rowson-Parr Virus in Mice. I. Growth Curves of Rowson-Parr Virus and Immunological Relationships with Friend Virus
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The growth curve of Rowson-Parr virus (RPV) was studied in the spleen of mice infected with RPV only and of mice infected with Friend virus (FV) preparations, which consist of a mixture of RPV and FV. In mice infected with FV preparations, RPV replicated to a higher titer than FV and attained higher levels than in singly infected mice. The chronic viremia of RPV-infected mice was found to coexist with circulating anti-RPV antibodies. These antibodies also neutralize FV and are probably responsible for the resistance against FV conferred to mice by prior infection with RPV.
Title: Immunodepression by Rowson-Parr Virus in Mice. I. Growth Curves of Rowson-Parr Virus and Immunological Relationships with Friend Virus
Description:
The growth curve of Rowson-Parr virus (RPV) was studied in the spleen of mice infected with RPV only and of mice infected with Friend virus (FV) preparations, which consist of a mixture of RPV and FV.
In mice infected with FV preparations, RPV replicated to a higher titer than FV and attained higher levels than in singly infected mice.
The chronic viremia of RPV-infected mice was found to coexist with circulating anti-RPV antibodies.
These antibodies also neutralize FV and are probably responsible for the resistance against FV conferred to mice by prior infection with RPV.
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