Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Comparing the Effects of Intrathecal Buprenorphine versus Fentanyl as Adjuvant to Hyperbaric Ropivacaine in Lower Limb Surgeries
View through CrossRef
Background: Subarachnoid block is often the choice of anaesthesia for lower limb surgeries. Hyperbaric Ropivacaine, a newer commercially available local anaesthetic preparation, offers faster recovery and fewer cardiovascular effects than bupivacaine but has a shorter duration of action. To prolong anaesthesia and postoperative analgesia, opioids such as fentanyl and buprenor-phine are used as adjuvants to local anaesthetics.Aim: This study aimed to compare the efficacy and safety of intrathecal buprenorphine versus fen-tanyl as adjuvants to hyperbaric ropivacaine in lower limb surgeries.Material and Methods: A prospective, double-blinded, randomised controlled trial was carried out in 76 patients, aged 18–60 years, belonging to ASA I and II and scheduled for lower limb pro-cedures under subarachnoid block. Patients were randomly allocated into two groups: Group B was given 3 ml of 0.75% hyperbaric ropivacaine with 0.5 ml buprenorphine (150 mg), while Group F got the same dose of ropivacaine with 0.5 ml fentanyl (25 mg). Parameters assessed included onset,level, sensory and motor block duration, changes in the haemodynamics, postoperative analgesia, and side effects.Results: Group F showed a significantly faster onset (p=<0.001) and time to reach maximum sensory level (p=<0.001). However, Group B had a significantly prolonged duration of sensory block and analgesia (p=<0.001). Group B demonstrated better haemodynamic stability, with fewer episodes of hypotension and bradycardia, though not statistically significant. Onset of motor block was faster, but duration was shorter in Group B. Minor side effects like pruritus and urinary reten-tion were more frequent in Group B.Conclusion: Buprenorphine as an intrathecal adjuvant to hyperbaric ropivacaine provides superior postoperative analgesia, prolonged sensory block, and better hemodynamic stability than fentanyl, making it a preferable choice for lower limb surgeries.
Sri Lanka Journals Online
Title: Comparing the Effects of Intrathecal Buprenorphine versus Fentanyl as Adjuvant to Hyperbaric Ropivacaine in Lower Limb Surgeries
Description:
Background: Subarachnoid block is often the choice of anaesthesia for lower limb surgeries.
Hyperbaric Ropivacaine, a newer commercially available local anaesthetic preparation, offers faster recovery and fewer cardiovascular effects than bupivacaine but has a shorter duration of action.
To prolong anaesthesia and postoperative analgesia, opioids such as fentanyl and buprenor-phine are used as adjuvants to local anaesthetics.
Aim: This study aimed to compare the efficacy and safety of intrathecal buprenorphine versus fen-tanyl as adjuvants to hyperbaric ropivacaine in lower limb surgeries.
Material and Methods: A prospective, double-blinded, randomised controlled trial was carried out in 76 patients, aged 18–60 years, belonging to ASA I and II and scheduled for lower limb pro-cedures under subarachnoid block.
Patients were randomly allocated into two groups: Group B was given 3 ml of 0.
75% hyperbaric ropivacaine with 0.
5 ml buprenorphine (150 mg), while Group F got the same dose of ropivacaine with 0.
5 ml fentanyl (25 mg).
Parameters assessed included onset,level, sensory and motor block duration, changes in the haemodynamics, postoperative analgesia, and side effects.
Results: Group F showed a significantly faster onset (p=<0.
001) and time to reach maximum sensory level (p=<0.
001).
However, Group B had a significantly prolonged duration of sensory block and analgesia (p=<0.
001).
Group B demonstrated better haemodynamic stability, with fewer episodes of hypotension and bradycardia, though not statistically significant.
Onset of motor block was faster, but duration was shorter in Group B.
Minor side effects like pruritus and urinary reten-tion were more frequent in Group B.
Conclusion: Buprenorphine as an intrathecal adjuvant to hyperbaric ropivacaine provides superior postoperative analgesia, prolonged sensory block, and better hemodynamic stability than fentanyl, making it a preferable choice for lower limb surgeries.
Related Results
To compare the efficacy of intrathecal 0.75% heavy ropivacaine and 0.5% heavy bupivacaine for lower abdominal and lower limb surgery
To compare the efficacy of intrathecal 0.75% heavy ropivacaine and 0.5% heavy bupivacaine for lower abdominal and lower limb surgery
Background: Spinal anesthesia is the most popular regional anesthesia technique for lower limb and lower abdominal surgery. Bupivacaine 0.5% heavy is commonly used for intrathecal ...
To compare the efficacy of intrathecal 0.75% heavy ropivacaine and 0.5% heavy bupivacaine for lower abdominal and lower limb surgery
To compare the efficacy of intrathecal 0.75% heavy ropivacaine and 0.5% heavy bupivacaine for lower abdominal and lower limb surgery
Background: Spinal anesthesia is the most popular regional anesthesia technique for lower limb and lower abdominal surgery. Bupivacaine 0.5% heavy is commonly used for intrathecal ...
A randomized and clinical study comparing spinal anesthesia with hyperbaric bupivacaine with fentanyl and hyperbaric ropivacaine with fentanyl in cesarean sections
A randomized and clinical study comparing spinal anesthesia with hyperbaric bupivacaine with fentanyl and hyperbaric ropivacaine with fentanyl in cesarean sections
Background: Hyperbaric bupivacaine (0.5%) is usually effective for spinal anesthesia and is being increasingly used in cases of patients undergoing lower segment cesarean section u...
A comparative study of efficacy of ropivacaine (0.75%) with adjuvants – dexmedetomidine and fentanyl in supraclavicular brachial plexus block
A comparative study of efficacy of ropivacaine (0.75%) with adjuvants – dexmedetomidine and fentanyl in supraclavicular brachial plexus block
Background: Brachial plexus block is preferred to general anesthesia (GA) as it reduces many complications of GA, provides good intra and postoperative analgesia, adequate muscle r...
Comparison of the postoperative analgesic effects of intrathecal Clonidine and Fentanyl as adjuvant: Mata Analysis of randomized control trials
Comparison of the postoperative analgesic effects of intrathecal Clonidine and Fentanyl as adjuvant: Mata Analysis of randomized control trials
Abstract
Background: Intrathecal clonidine and fentanyl added to bupivacaine prolongs the postoperative analgesic effects for below umbilicus surgery. However, the overall ...
COMPARATIVE STUDY OF CLONIDINE AND FENTANYLAS ADJUVANTS TO INTRATHECAL ROPIVACAINE TO ASSESS THE DURATION OF ANALGESIA IN LOWER LIMB SURGERIES.
COMPARATIVE STUDY OF CLONIDINE AND FENTANYLAS ADJUVANTS TO INTRATHECAL ROPIVACAINE TO ASSESS THE DURATION OF ANALGESIA IN LOWER LIMB SURGERIES.
Objective: Ropivacaine has the benet of providing appropriate intraoperative anaesthesia and effective postoperative analgesia when used for lower limb procedures under spinal ana...
Evaluation of Analgesic Efficacy of Intrathecal Buprenorphine versus Tramadol as Adjuvants to Bupivacaine: A Comparative Study
Evaluation of Analgesic Efficacy of Intrathecal Buprenorphine versus Tramadol as Adjuvants to Bupivacaine: A Comparative Study
Background: Intrathecal adjuvants are widely used to enhance the quality and duration of spinal anaesthesia, especially in infra-umbilical surgeries. Buprenorphine, a partial μ-opi...
Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl
Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl
ImportanceBuprenorphine treatment of opioid use disorder (OUD) is safe and effective, but opioid withdrawal during treatment initiation is associated with poor retention in care. A...