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3.2.3 Coupling via C(sp3)—H Activation under Palladium Catalysis

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AbstractThis chapter describes the synthetic and mechanistic aspects of palladium-catalyzed arylation, carbonylation, alkenylation, and alkylation of C(sp3)—H bonds. Recent accomplishments in the enantioselective construction of C(sp3)—C bonds via C(sp3)—H activation are also detailed. Additionally, the few reported examples of the strategic application of these powerful C(sp3)—C bond forming transformations toward complex molecule synthesis are presented.
Title: 3.2.3 Coupling via C(sp3)—H Activation under Palladium Catalysis
Description:
AbstractThis chapter describes the synthetic and mechanistic aspects of palladium-catalyzed arylation, carbonylation, alkenylation, and alkylation of C(sp3)—H bonds.
Recent accomplishments in the enantioselective construction of C(sp3)—C bonds via C(sp3)—H activation are also detailed.
Additionally, the few reported examples of the strategic application of these powerful C(sp3)—C bond forming transformations toward complex molecule synthesis are presented.

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