Herbal Drug in Parkinson’s Disease

Abstract: A neurological condition with multiple levels of intricacy is Parkinson's disease. It has long been distinguished by the loss of dopaminergic neurons in the substantia nigra and the conventional motor characteristics of parkinsonism linked to Lewy bodies. Nonetheless, it is now acknowledged that Parkinson's disease symptoms can vary widely and include non-motor characteristics that are clinically significant. Its disease also includes protein aggregates other than Lewy bodies, other neurotransmitters, and large areas of the nervous system. Although the exact origin of Parkinson's disease is still unknown, environmental influences are no longer thought to be the key contributing factor. Rather, a complex interaction between environmental and genetic factors that impact many basic cellular functions appears to be the cause of Parkinson's disease. Clinical difficulties associated with the intricacy of Parkinson's disease include the inability to make a conclusive diagnosis in the early stages of the illness and challenges managing symptoms later on. Moreover, the neurodegenerative process cannot be slowed by any treatment. One of the most prevalent nonmotor side effects of Parkinson's disease (PD) is sleep disturbance, which becomes more frequent as the condition worsens. There are many different reasons why people with Parkinson's disease experience sleep disturbances, and many individuals may have multiple contributing variables. These conditions can be roughly divided into two groups: those that affect sleep at night and those that show up during the day as excessive daytime sleepiness. Key words : Parkinson disease, Mucuna pruriens, ginseng, Silymarin, Astragalus